A team of scientists from N.I. Lobachevsky State University of Nizhny Novgorod, Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, a company Amplituda Science and Technology Centre, and other research groups, has developed a combined action drug based on ionizing radiation and bacterial toxin.
The drug affects tumor cells selectively providing better diagnostics and treatment of malignant tumors. The drug consists of nano particles, as the core, with embedded radio pharmaceutical agent (a source of ionizing beta-radiation), and a highly toxic toxin derived from bacterium Pseudomonas aeruginosa.
The radio pharmaceutical agent is well secluded inside the nano particle and guarantees its side-effect-free targeted action to tumor cells.
The scientists observed that the drug not only treats, but also facilitates visualisation of the tumors, which makes it a diagnostic tool.